GCSE · Biology · Edexcel · Spec 1BI0

Hormones and endocrine glands

Hormones travel in your blood, so why doesn't every organ react to every hormone? It is all about who is listening.

Find the glands

The endocrine glands
PituitaryAdrenal glandsOvariesThyroidPancreasTestes

Showing 4 layers: Body outline, Kidneys (for reference), Glands, Names

Layers

Explore

Switch the names off, then see if you can still place every gland.

The kidneys are drawn only so you can see what the adrenal glands sit on top of.

Select a gland to see where it sits, which hormone it secretes and what that hormone controls. Ovaries are found in females and testes in males; this outline shows both so you can compare.

Check your picture

How does a hormone find its target?

A gland secretes a hormone. Some organs respond to it. Other organs do not.

Which of these is closest to what you think is going on?
How sure are you?

Why "master"?

?

Reason it through

Why is the pituitary gland called the master gland?

Link 1 of 4

First link · your turn

Start in the brain. What does the pituitary gland secrete that is aimed at another gland?

2
Locked — reveal the link above first
3
Locked — reveal the link above first
4
Locked — reveal the link above first

When nerves set a hormone off

Four steps, in order. The first three are nervous; the last is endocrine.

  1. A stimulus is detectedReceptors detect a change (a stimulus).
  2. Impulses go to the brainThe receptors send electrical impulses along neurones to the brain.
  3. The brain signals a glandThe brain can send impulses to a gland.

Two control systems

Nervous systemvsEndocrine system

The speed row is the one people swap round.

Focus

How it carries the message

Nervous system

Electrical impulses along nerves

Endocrine system

Hormones in the blood

The insight

One system sends electricity along nerves. The other sends chemicals through the blood.

How fast it acts

Nervous system

Quickly

Endocrine system

Slower to act

How long the effect lasts

Nervous system

Short-lived responses

Endocrine system

Longer-lasting effects

How they work together

Nervous system

Works with the endocrine system to regulate body conditions

Endocrine system

Works with the nervous system to regulate body conditions

Your turn

Write it, then mark it

Adrenaline is secreted by the adrenal glands. Explain why adrenaline affects some organs but not others. [3 marks]

0 words · your answer stays on this page and is not sent anywhere.

WHAT YOU'VE LEARNED

A quick recap of today's lesson.

Chemical messengers that travel in your blood, and only some cells are listening.

What you need to know

  • The endocrine system is made up of glands that secrete hormones into the blood.
  • A hormone is a chemical made by a gland. It travels in the blood to a specific target organ.
  • Hormones are transported in the blood plasma to their target organs.
  • Cells of a target organ have specific receptors on their surface, and the hormone binds to them.
  • Other organs' cells lack the matching receptor, so the hormone does not act on them.
  • Have a goA classmate says: "A hormone is posted to its target organ like a parcel, and no other organ ever gets a look in." What carries a hormone, and what decides which organs respond?

    The blood plasma carries it; matching receptors on the cells decide who responds.

    Nothing is "addressed". The hormone is carried in the plasma, and the receptor on the receiving cell is what makes an organ a target.

  • Endocrine glands include the pituitary (brain), thyroid (neck), pancreas, adrenal glands (on top of the kidneys), ovaries (females) and testes (males).
  • The pituitary is the master gland: TSH from the pituitary stimulates the thyroid gland to make thyroxine.
  • Have a goTrue or false: the thyroid gland secretes TSH, which tells the pituitary what to do.

    False. The pituitary secretes TSH, and TSH stimulates the thyroid.

    The instruction runs the other way: the pituitary's hormone acts on the thyroid, which is why the pituitary is the master gland.

  • Thyroxine controls metabolic rate, adrenaline prepares the body for fight or flight, and insulin and glucagon regulate blood glucose concentration.
  • The nervous system can trigger hormone secretion: the brain can send impulses to a gland.
  • Nerves act quickly with short-lived responses. Hormones are slower to act but longer-lasting, and the two systems work together.
  • Have a goAnother classmate: "Hormones are slower than nerves, so they must be the weaker system." Give one fact that shows why this is not the full picture.

    Hormone effects are longer-lasting, and the two systems work together.

    Slower to act does not mean less important: the effects last longer, and both systems work together to regulate body conditions.

The big picture

The endocrine system is a set of glands that secrete hormones into the blood. Hormones are carried in the plasma, and a hormone acts on target organs whose cells have the matching receptor. The pituitary is the master gland, and the nervous and endocrine systems work together.

Key points

1Route of a hormone: gland, then blood plasma, then target organ.
2A hormone acts on organs whose cells have the matching receptor, and not on organs whose cells lack it.
3The pituitary is the master gland because its hormones make other glands secrete further hormones.
4Thyroxine: metabolic rate. Adrenaline: fight or flight. Insulin and glucagon: blood glucose concentration.
5Oestrogen (ovaries) and testosterone (testes) control the development of secondary sex characteristics.
6Nerves: quick and short-lived. Hormones: slower and longer-lasting. Together they regulate body conditions.

Worked example

Problem

You hear a sudden bang and jump. A minute later you still feel ready for fight or flight. Use ideas about the nervous system and the endocrine system to explain the quick jump and the lingering feeling.

⚠ Watch out

In an answer, don't write that a hormone is "sent to" or "goes straight to" an organ. Write that it is secreted into the blood, transported in the plasma, and binds to the matching receptors on the cells of the target organ.

🧠

Memory hook

Hormone = a key carried in the blood. Receptor = the lock. Only a cell with the matching lock responds. Pituitary = the head teacher giving orders to other glands.

✓

Check yourself

Sketch a body and place all six glands. Then pick one and tell its whole story aloud: hormone, job, and why only some organs respond.

Flashcards

(12)
What is the endocrine system made up of?
Glands that secrete hormones into the blood.
What is a hormone?
A chemical substance produced by a gland. It travels in the bloodstream to a specific target organ, where it brings about an effect.
What carries hormones to their target organs?
The blood plasma.
Why does a hormone act on its target organ and not on other organs?
Target organ cells have specific receptors on their surface that the hormone binds to. Other organs' cells lack the matching receptor.
Name the endocrine glands on the map.
Pituitary (brain), thyroid (neck), pancreas, adrenal glands (on top of the kidneys), ovaries (females), testes (males).
Which gland is the master gland, and what does it do?
The pituitary. Its hormones act on other glands to make them secrete further hormones.
Which gland secretes thyroxine, and what does thyroxine control?
The thyroid gland. Thyroxine controls the metabolic rate of the body.
Which glands secrete adrenaline, and what does it do?
The adrenal glands. Adrenaline prepares the body for fight or flight.
Which gland secretes insulin and glucagon?
The pancreas. They regulate blood glucose concentration.
What does oestrogen control?
Secreted by the ovaries. It controls the development of female secondary sex characteristics and plays a role in the menstrual cycle.
What does testosterone control?
Secreted by the testes. It controls the development of male secondary sex characteristics and the production of sperm.
Nervous system versus endocrine system: speed and duration?
Nervous: quick, short-lived responses. Endocrine: slower to act, longer-lasting effects. The two work together to regulate body conditions.

Tap any card to flip it, or use Study as deck to go through them one at a time. In the full lesson these run as a spaced-repetition deck — you rate each card Hard, Good or Easy and the tricky ones keep coming back until they stick.

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