GCSE · Biology · Edexcel · Spec 1BI0
Hormones and endocrine glands
Hormones travel in your blood, so why doesn't every organ react to every hormone? It is all about who is listening.
Find the glands
Layers
Explore
Switch the names off, then see if you can still place every gland.
The kidneys are drawn only so you can see what the adrenal glands sit on top of.
Select a gland to see where it sits, which hormone it secretes and what that hormone controls. Ovaries are found in females and testes in males; this outline shows both so you can compare.
Why "master"?
Reason it through
Why is the pituitary gland called the master gland?
First link · your turn
Start in the brain. What does the pituitary gland secrete that is aimed at another gland?
When nerves set a hormone off
Four steps, in order. The first three are nervous; the last is endocrine.
- A stimulus is detectedReceptors detect a change (a stimulus).
- Impulses go to the brainThe receptors send electrical impulses along neurones to the brain.
- The brain signals a glandThe brain can send impulses to a gland.
WHAT YOU'VE LEARNED
A quick recap of today's lesson.
Chemical messengers that travel in your blood, and only some cells are listening.
What you need to know
- The endocrine system is made up of glands that secrete hormones into the blood.
- A hormone is a chemical made by a gland. It travels in the blood to a specific target organ.
- Hormones are transported in the blood plasma to their target organs.
- Cells of a target organ have specific receptors on their surface, and the hormone binds to them.
- Other organs' cells lack the matching receptor, so the hormone does not act on them.
Have a goA classmate says: "A hormone is posted to its target organ like a parcel, and no other organ ever gets a look in." What carries a hormone, and what decides which organs respond?
The blood plasma carries it; matching receptors on the cells decide who responds.
Nothing is "addressed". The hormone is carried in the plasma, and the receptor on the receiving cell is what makes an organ a target.
- Endocrine glands include the pituitary (brain), thyroid (neck), pancreas, adrenal glands (on top of the kidneys), ovaries (females) and testes (males).
- The pituitary is the master gland: TSH from the pituitary stimulates the thyroid gland to make thyroxine.
Have a goTrue or false: the thyroid gland secretes TSH, which tells the pituitary what to do.
False. The pituitary secretes TSH, and TSH stimulates the thyroid.
The instruction runs the other way: the pituitary's hormone acts on the thyroid, which is why the pituitary is the master gland.
- Thyroxine controls metabolic rate, adrenaline prepares the body for fight or flight, and insulin and glucagon regulate blood glucose concentration.
- The nervous system can trigger hormone secretion: the brain can send impulses to a gland.
- Nerves act quickly with short-lived responses. Hormones are slower to act but longer-lasting, and the two systems work together.
Have a goAnother classmate: "Hormones are slower than nerves, so they must be the weaker system." Give one fact that shows why this is not the full picture.
Hormone effects are longer-lasting, and the two systems work together.
Slower to act does not mean less important: the effects last longer, and both systems work together to regulate body conditions.
The big picture
The endocrine system is a set of glands that secrete hormones into the blood. Hormones are carried in the plasma, and a hormone acts on target organs whose cells have the matching receptor. The pituitary is the master gland, and the nervous and endocrine systems work together.
Key points
Worked example
Problem
You hear a sudden bang and jump. A minute later you still feel ready for fight or flight. Use ideas about the nervous system and the endocrine system to explain the quick jump and the lingering feeling.
⚠ Watch out
In an answer, don't write that a hormone is "sent to" or "goes straight to" an organ. Write that it is secreted into the blood, transported in the plasma, and binds to the matching receptors on the cells of the target organ.
Memory hook
Hormone = a key carried in the blood. Receptor = the lock. Only a cell with the matching lock responds. Pituitary = the head teacher giving orders to other glands.
Check yourself
Sketch a body and place all six glands. Then pick one and tell its whole story aloud: hormone, job, and why only some organs respond.
Flashcards
(12)What is the endocrine system made up of?
What is a hormone?
What carries hormones to their target organs?
Why does a hormone act on its target organ and not on other organs?
Name the endocrine glands on the map.
Which gland is the master gland, and what does it do?
Which gland secretes thyroxine, and what does thyroxine control?
Which glands secrete adrenaline, and what does it do?
Which gland secretes insulin and glucagon?
What does oestrogen control?
What does testosterone control?
Nervous system versus endocrine system: speed and duration?
Tap any card to flip it, or use Study as deck to go through them one at a time. In the full lesson these run as a spaced-repetition deck — you rate each card Hard, Good or Easy and the tricky ones keep coming back until they stick.
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